TRP channels in endothelial function and dysfunction
نویسندگان
چکیده
منابع مشابه
TRP channels in endothelial function and dysfunction.
Endothelial cells produce various factors that regulate vascular tone, vascular permeability, angiogenesis, and inflammatory responses. The dysfunction of endothelial cells is believed to be the major culprit in various cardiovascular diseases, including hypertension, atherosclerosis, heart and renal failure, coronary syndrome, thrombosis, and diabetes. Endothelial cells express multiple transi...
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Another TRP to Endothelial Dysfunction : TRPM2 and Endothelial Permeability Print ISSN: 0009-7330. Online ISSN: 1524-4571 Copyright © 2008 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation Research doi: 10.1161/CIRCRESAHA.107.170548 2008;102:275-277 Circ Res. http://circres.ahajournals.org/c...
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Sustained elevation in the intracellular Ca concentration via Ca influx, which is activated by a variety of mechanisms, plays a central regulatory role for cardiovascular functions. Recent molecular biological research has disclosed an unexpectedly diverse array of Ca -entry channel molecules involved in this Ca influx. These include more than ten transient receptor potential (TRP) superfamily ...
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Urotensin-II (U-II), the most potent vasoconstrictor that has recently been recognized as a new candidate in cardiovascular dysfunction, might exert vasoconstriction through, at least partially, potassium channels that are predominant in both endothelial and vascular smooth muscle cells (VSMCs). The present study was designed to evaluate the roles of potassium channels in vascular responses to ...
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Recent years have seen great advances in the molecular description of sensory neurobiology. Of the five popularly characterized senses (sight, hearing, taste, smell and touch), touch is perhaps the most varied and least understood. Within this modality is the ability to sense mechanical forces, chemical stimuli, and temperature, and the molecules that mediate this ability have been a long-stand...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
سال: 2007
ISSN: 0925-4439
DOI: 10.1016/j.bbadis.2007.02.013